Time domain NMR (TD-NMR) is a method to analyze samples using magnetic resonance. There are multiple advantages of TD-NMR.
The duration or lifetime of signals typically differ in the following way. Crystalline solids usually decay very quickly for tens of microseconds. Non-crystalline solids or amorphous materials have signals which usually last slightly longer, perhaps 100 to 200 microseconds, followed by semisolids like rubber and other soft materials, which might last for a few milliseconds and finally liquids have signals which can last for seconds. Sampling the signal of a mixture of materials at different points reflects the concentration of each species. The figure below illustrates the differentiation of solid fat (a crystalline material) and liquid fat. There are two measurements at 11 µsec (the total signal) and 70 µsec (liquid signal).
The decay behavior of the signal can also serve to characterize the authenticity of the sample. For crystalline materials, changes in crystal packing due to processing have been found to correlate well with x-ray powder diffraction measurements. A pulsed NMR instrument presents no adverse health risks, therefore it can be a preferred technique in production environment.
TD-NMR instruments are proton counting instruments. Since each hydrogen (1H) responds the same as other hydrogens regardless of the structure (unlike methods like UV-Visible), TD-NMR is excellent for characterizing mixtures.
The choice of the system is determined by application.
Find more info about NMR Applications
specfit and LAIX technologies partner to automate the operation of either the HR27 or HR50. The robot is capable of working with dry tempering baths, an analytical balance, and other lab equipment for sample preparation. For more information, see the Fat Lab page for more ideas. Contact us for a custom solution for your laboratory.
specfit can swap probes to accommodate a broad range of sample sizes customized for a particular application.
Results in seconds not hours by non-technical personnel
Eliminate extraction and the use of organic solvents
Minimum sample prep weigh and GO!
Compatible with reporting software for integration of results in automated record keeping and corporate information systems.